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Jim Goodwin
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jgoodwin@missouricures.org




 

 

 


Awards galore and much more

HADASSSAH IS HOSTING A BIG STEM CELL RELATED EVENT on Feb. 14, this one of particular interest in advances against Multiple Sclerosis (MS). In case you had not noticed, the event falls on Valentine's Day and is called "Framing the Future Encore: A Love Story." It will feature an inspiring story from a MS patient from Houston and her husband.

Embryonic stem cells improve vision for two women

Two women with untreatable eye diseases said they had dramatic improvements in their vision after injections of human embryonic stem cells, making it the first documented time these controversial cells have helped someone.

BrainStorm Sees Positive Data in ALS Stem Cell Trial

Data from the first ALS patients in a clinical trial treated with BrainStorm Cell Therapeutics adult stem cell therapy did not show significant side effects and the treatment has so far proven to be safe, the company said on Tuesday.

Leading Eye Institute to Participate in ACT's Embryonic Stem Cell Clinical Trial for Macular Degeneration

Wills Eye Institute receives IRB approval to treat dry-AMD using ACT's hESC-derived retinal pigment epithelial (RPE) cells.

British Scientists in New Medical Breakthrough to Grow 'Off the Shelf Veins'

A medical breakthrough by British scientists to grow "off the shelf" veins and arteries, which could potentially revolutionise treatment for range of conditions, has been hailed.

Cell Search for Key to Dementia

A research project designed to help develop new treatments to replace brain cells lost during dementia is being launched at Nottingham University.

University of Kentucky Offers Stroke Stem Cell Trial

The University of Kentucky will be the first site in the state and one of a select few in the entire country participating in the first stages of a groundbreaking study to investigate the effects of MultiStem, a human adult stem cell product, on patients with acute ischemic stroke.

First FDA-Approved Study of Stem Cells to Treat Hearing Loss Begins at Children's Memorial Hermann Hospital

Children's Memorial Hermann Hospital and Cord Blood Registry® (CBR) are launching the first FDA-approved, Phase I safety study on the use of cord blood stem cells to treat children with sensorineural hearing loss.

Scientists Learn How Stem Cell Implants Help Heal Traumatic Brain Injury

For years, researchers seeking new therapies for traumatic brain injury have been tantalized by the results of animal experiments with stem cells.

Synthetic Windpipe Is Used to Replace Cancerous One

The windpipe, or trachea, made from minuscule plastic fibers and covered in stem cells taken from the man's bone marrow, was implanted in November. The patient, Christopher Lyles, 30, whose tracheal cancer had progressed to the point where it was considered inoperable, arrived home in Baltimore on Wednesday. It was the second procedure of its kind and the first for an American.

Treatment Offers Diabetes Sufferers Hope

The dream of reducing -- even eliminating -- daily insulin injections may become reality for people with Type 1 diabetes by treating the cause of the debilitating disease instead of its effects.

Age-related Effect of MS may be Reversible

U.S. and British researchers report their work with mice indicates the myelin sheath surrounding nerves lost to multiple sclerosis may be partially rejuvenated.

Stem Cells in Eyes Offer Hope for Reversing Leading Cause of Blindness in Seniors

Eyes have been called the window to the soul, but they are also proving to be a potential wellspring for regenerative medicine.

AlloCure's Investigational Treatment for Acute Kidney Injury Receives Fast Track Designation by FDA

AlloCure, Inc., a clinical stage biotechnology company focused on the treatment of kidney disease, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to AC607, the company's investigational treatment for acute kidney injury (AKI).

How to Regrow a Limb

The loss of a human limb is a tragedy. We know that once they're gone, mammalian arms and legs can't ever be restored. But if you cut off a salamander's leg -- or tail -- it will reappear in just a few weeks.

Athersys Gets U.S. Stem Cell Patent for Heart Attack, Other Conditions

Athersys has obtained a U.S. patent that covers the use of nonembryonic multi-potent stem cells for the treatment of several heart conditions, including heart attack.

BioTime to Produce Stem Cells for Research in Muscle Disorders

BioTime, Inc. today announced that it has elected to market progenitors of muscle stem cells bearing hereditary diseases.

Age-Related Degeneration Can Be Caused by Defects of Energy Metabolism in Tissue Stem Cells

New findings by researchers at the University of Helsinki, Finland, increase the understanding of mechanisms of age-related degeneration. The results are a breakthrough in revealing the unexpected importance of energy metabolism in regulating stem cell function and tissue maintenance.

Stem Cell Shots Reverse Aging in Mice

Injecting younger cells into aging bodies could help people live longer -- and stronger -- at least according to new research performed on mice.

Researchers Hope Stem Cell Therapy will Reverse Stroke Effects

When stroke patients do not receive immediate care the chances of suffering paralysis, disturbances to speech and impaired vision increase. A new stem cell therapy aims to reverse the effects a stroke has on the body.

Stem Cell Treatment to Prevent Hearing Loss

Stem cells which could help combat hearing loss associated with old-age are being developed by British scientists, in the first study of its kind.

Israeli Researchers Use Stem Cells to Repair Damaged Tissue for First Time

Mice who suffered from insufficient blood flow regained almost full muscle function; researchers say method may be usable to repair human tissue, organs in future.

Kyoto Research Team to Create Stem Cell Bank

A research team here has announced its plans to create a stem cells bank that will preserve artificially created stem cells to be used in regenerative medicine, it has been revealed.

Stem Cell Research Yields Blood Restoring Vessels

Heart attack, stroke treatment to benefit from Israeli breakthrough.

Artificial Intestines Come Closer to Reality

A new artificial intestine developed in a laboratory using collagen and stem cells, is expected to soon help treat people suffering from acute bowel disorders.

Latest Victory For Regenerative Medicine: Pituitary Grown From Embryonic Stem Cells

Chalk up another part of the body that can be grown from stem cells at least in mice. Scientists in Japan have induced mouse embryonic stem cells to form a pituitary in the lab.

JDRF to Support ViaCyte's Development of Innovative Encapsulated Beta Cell Replacement Therapy for Diabetes

Goal of new JDRF research is to restore insulin production in people with type 1 diabetes.

Denver Spine Physicians Begin Enrollment in United States Stem Cell Therapy Study

DenverSpine today announced that it has enrolled its first patient in a nationwide FDA-cleared adult stem cell study testing novel treatment for chronic low back pain.

Therapy Improves Stem Cell Engraftment In Umbilical Cord Blood Transplant Recipients

A therapy involving a natural compound may improve the ability of stem cells from umbilical cord blood to engraft in patients receiving a stem cell transplant for cancer or other diseases, a phase I clinical trial led by Dana-Farber Cancer Institute scientists indicates.

Healing Serious Bone Injuries Faster Than Ever Before

A human-made package filled with nature's bone-building ingredients delivers the goods over time and space to heal serious bone injuries faster than products currently available, Cleveland researchers have found.

Team Develops Method to Form Blood Platelets from Stem Cells

A team of researchers from Kyoto University and the University of Tokyo has worked out a method using artificially created stem cells to produce a large volume of cells from which blood platelets can be derived outside the human body.

Pancreas Study Offers Diabetes Hope

Research into a rare genetic disorder of the pancreas may speed up progress towards stem cell treatments for diabetes, according to researchers.

Cellular Automaton Model Predicts How Hair Follicle Stem Cells Regenerate

Your hair -- or lack of hair -- is the result of a lifelong tug-of-war between activators that wake up, and inhibitors that calm, stem cells in every hair follicle on your body, according to Cheng-Ming Chuong, M.D., Ph.D., of the University of Southern California (USC).

'Gold Standard' Embryonic Stem Cell Lines Developed

Researchers from King's College London have produced the first animal product-free clinical grade human embryonic stem cell lines.

Salk Researchers Develop Safe Way to Repair Sickle Cell Disease Genes

New gene editing technique would heal patients with their own cells.

Research Could Help People With Declining Sense of Smell

University of California, Berkeley, neuroscientists have discovered a genetic trigger that makes the nose renew its smell sensors, providing hope for new therapies for people who have lost their sense of smell due to trauma or old age.

Stem Cell Research may Help Those with Osteoarthritis

David Bauman is still walking with a cane. He had one knee replaced in January, and a total hip replacement in October.

Spatiotemporal Signals Guide Stem Cell Changes Enabling Engineering Of Cartilage Replacements

A lab discovery is a step toward implantable replacement cartilage, holding promise for knees, shoulders, ears and noses damaged by osteoarthritis, sports injuries and accidents.

U-M Researchers Use Stem Cells to Gain New Insight into Severe Childhood Form of Epilepsy

Team investigating causes of Dravet syndrome presents new approach to understanding the syndrome to American Epilepsy Society.

MS Bone Marrow Stem Cell Trial to Begin

British doctors are to conduct a trial using bone marrow stem cells that they hope could halt or perhaps even reverse the progression of multiple sclerosis (MS).

Lab-grown Glands, Eyes and Brain Parts

A group of Japanese researchers is at the forefront of the quest to grow complete organs in the lab.

Scalable Amounts of Liver and Pancreas Precursor Cells Created Using New Stem Cell Production Method

Technique should help research into pre-clinical and clinical evaluation of cells.

Asthma Researcher Theorizes about 'Healing Juices' of Stem Cells

The medical benefits of stem cells may lie in their "healing juice" by-products, says an University of Alberta pediatric asthma researcher.

Stem Cell Promise for Multiple Sclerosis

New research has found a way to replenish the fatty layer or myelin sheath around nerve cells1 -- a finding that could yield a cure for neurodegenerative diseases such as multiple sclerosis.

Adult Stem Cells Use Special Pathways To Repair Damaged Muscle, MU Researchers Find

When a muscle is damaged, dormant adult stem cells called satellite cells are signaled to "wake up" and contribute to repairing the muscle. University of Missouri researchers recently found how even distant satellite cells could help with the repair, and are now learning how the stem cells travel within the tissue.

Stem Cells Traced To Heart

New research suggests that a controversial class of stem cells originates in the heart and retains some ability to repair damaged tissue.

Neurons Created That Light Up As They Fire

In a scientific first that potentially could shed new light on how signals travel in the brain, how learning alters neural pathways, and might lead to speedier drug development, scientists at Harvard have created genetically-altered neurons that light up as they fire.

Scientists Induce Pluripotent Stem Cells From Pompe Disease Patients

Taiwanese researchers have successfully induced the world's first pluripotent stem cells from the skin cells of Pompe disease patients.

Cell Culture Startup's Scaffold Used in 2nd-ever Synthetic Trachea Transplant

A two-year-old Ohio State University spinoff's nanofiber scaffold was used to grow a patient's own stem cells and then implanted into the patient after his trachea was removed -- in an operation that's being billed as the world's second successful synthetic trachea transplant.

Stem Cells Engineered to Kill Cancer

U.S. researchers say they've shown that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma.

Body Rebuilding: Scientists Regenerate Muscle in Mice

New study uses reprogrammed human cells and bioengineered microthreads.

Aging Stem Cells May Explain Higher Prevalence of Leukemia, Infections Among Elderly

Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood and immune system. Understanding when and how these stem cells begin to falter as the years pass may explain why some diseases, such as acute myeloid leukemia, increase in prevalence with age, and also why elderly people tend to be more vulnerable to infections such as colds and the flu.

UCLA Researchers Engineer Blood Stem Cells to Fight Melanoma

Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers believe this approach could be useful in 40 percent of Caucasians with this malignancy.

Stem Cells Undergo Evolution in the Lab

A new study has found cultured human embryonic stem cells undergo selection for greater self-renewal, which has implications on stem cell therapies.

Defect In Brain Cell Channel Identified That May Cause Autism-Like Syndrome

Neuroscientists at Stanford University School of Medicine have homed in on potential differences in autistic people's brain cells by studying brainlike spheres grown in an elaborate process from skin cells.

DNA Discovery May Boost Stem Cell Safety

A region of DNA that can boost the growth of stem cells has been found in the largest ever study of human embryonic stem cells.

iPS Cells Created from 110-year-old People

Aiming to discover the key to longevity, a team of Keio University researchers has succeeded in creating induced pluripotent stem cells (iPS) from the blood of people aged 110 or older, it has been learned.

Second U.S. Patent Awarded to Stem Cell Idea of Kyoto Univ.'s Yamanaka

The United States has awarded a patent for Kyoto University professor Shinya Yamanaka's technology for creating induced pluripotent stem cells, or iPSCs, the second of its kind since the first patent for the technique was granted in August, the university said Thursday.

Stem-Cell-Seeded Bioartificial Tracheal Transplant Feasible

First-in-man bioengineered artificial tracheobronchial airway transplantation successful

Researchers Decode a Puzzling Movement Disorder

Neurodegenerative diseases represent one of the greatest challenges of our aging society.

Discovery of a New Muscle Repair Gene

An international team of researchers from England and the Charité -- Universitätsmedizin Berlin has presented new findings regarding the function of muscle stem cells, which are published in the current issue of the journal Nature Genetics. The researchers investigated several families with children suffering from a progressive muscle disease.

Researchers Create Spinal Cord Connectors from Human Stem Cells, Heralding Breakthrough

It's taken many years and more than a bit of brainpower, but researchers at the University of Central Florida have finally found a way to create neuromuscular connectors between muscle and spinal cord cells, using only stem cells.

First Human iPS Therapy Eyed in 2013

A clinical study into the use of lab-grown retina cells to treat age-related macular degeneration has been slated for fiscal 2013, a senior staffer of the research body planning to undertake the project said Saturday.

Landmark Spinal Repair Stem Cell Trial

The fifth and final patient in the Geron Corp sponsored trial of a human embryonic-stem-cell-derived treatment for severe spinal cord injury was treated on Nov. 16. at the Stanford University School of Medicine and Santa Clara Valley Medical Center.

Study to Look at Nerve Cells in Patients with Alzheimer's Disease

Researchers at the University of Bristol have been awarded a grant that by using state-of-the-art stem cell technology will enable them to analysis nerve cells produced from skin biopsies of patients with Alzheimer's disease (AD).

MSRCNY Receives Approval for Groundbreaking Stem Cell Trial in Multiple Sclerosis

Landmark study targets repair and regeneration for MS patients.

Success with Stem Cell Neurons

Light-controlled neurons made from human embryonic stem cells can activate neural circuits in mice.

Mending Hearts

As more people survive heart attacks, many of us are forced to live with the debilitating effects of heart failure. Now researchers hope to find a way to mend a broken heart.

Augusta Stem Cell Study May Help Treat Cerebral Palsy

It's a first for Augusta. Georgia Health Sciences University is conducting the first FDA regulated trial using stem cells.

Stem Cell Scientist Discusses New Drug Development Process

Pharmaceutical companies should turn to stem cells for a more effective and cost-efficient way to experiment with new medications, Harvard professor Lee L. Rubin said in a presentation yesterday.

New Heart Cells Increase by 30 Percent After Stem Cell Infusion

Healthy, new heart cells have been generated by animals with chronic ischemic heart disease after receiving stem cells derived from cardiac biopsies or "cardiospheres," according to research conducted at the University at Buffalo School of Medicine and Biomedical Sciences.

Stem Cell Study Helps Clarify the Best Time for Therapy to Aid Heart Attack Survivors

A research network led by a Mayo Clinic physician found that stem cells obtained from bone marrow delivered two to three weeks after a person has a heart attack did not improve heart function. This is the first study to systematically examine the timing and method of stem cell delivery and provides vital information for the field of cell therapy.

Stem Cells: New Hope for Heart Failure Patients

For the first time, stem cells from patients' own hearts have been shown to battle heart failure.

World's First Stem Cell Bandage in Human Clinical Trials

The company behind a pioneering stem cell bandage, believed to be the world's first adult and autologous (patient's own) stem cell treatment designed to heal torn meniscal cartilage, can now take the technology to human clinical trials thanks to an investment from one of the UK's most successful entrepreneurs.

For the First Time, Lab-Grown Blood Is Pumped Into a Human's Veins

Artificial blood may become a common reality, thanks to the first successful transfusion of lab-grown blood into a human. Luc Douay, of Pierre and Marie Curie University, Paris, extracted hematopoietic stem cells from a volunteer's bone marrow, and encouraged these cells to grow into red blood cells with a cocktail of growth factors. Douay's team labeled these cultured cells for tracing, and injected 10 billion of them (equalling 2 milliliters of blood) back into the marrow donor's body.

Biological Clock Controls Activation of Skin Stem Cells

A new study reveals the role of the daily biological clock (circadian rhythms) in the regenerative capacity of skin stem cells. Disruption of this rhythm results in premature tissue ageing and a greater predisposition to the development of skin tumours. The proper reestablishment of the biological clock increases the long-term regenerative capacity of the tissue and decreases the probability of developing tumours.

Mesoblast Posts Successful Results from Diabetes Stem Cell Trial

A pre-clinical animal trial of Mesoblast's (ASX:MSB) stem cell treatment for Type 2 diabetes has shown positive results, with phase II trial planned for 2012.

U.S. OK's Therapy Using Human Cord Blood Cells

U.S. drug regulators have for the first time approved a therapy that uses cells of human blood from the placenta and the umbilical cord to treat people with blood-forming disorders or cancer.

Skin Transformed for Cancer Fight

Scientists have opened up the possibility of one day using cancer patients' own skin to fight their tumours.

Researchers Create a Pituitary Gland from Scratch

The results could be an initial step toward generating viable, transplantable human organs.

Scientists 'Switch Off' Defective Genes in Cure for Skin Blistering Diseases

Scientists have taken major steps forward to curing severe skin blistering diseases like epidermolysis bullosa (EB) which ruin thousands of lives in the UK every year.

New Method for Making Neurons Could Lead to Parkinson's Treatment

When transplanted into rodents with brain damage similar to Parkinson's, the cells reversed the animals' motor issues.

Gene Therapy Shows Promise as Hemophilia Treatment in Animal Studies

For the first time, researchers have combined gene therapy and stem cell transplantation to successfully reverse the severe, crippling bleeding disorder hemophilia A in large animals, opening the door to the development of new therapies for human patients.

Pluristem Sees Positive Data from Stem Cell Trials

Pluristem Therapeutics had positive 12-month results from Phase I clinical trials for its PLX stem cells for the treatment of critical limb ischemia (CLI), the Israeli stem cell therapy company said on Thursday.

Reprogramming Stem Cells to a More Basic Form Results in More Effective Transplant, Study Shows

Chinese stem cell scientists have published new research that improves the survival and effectiveness of transplanted stem cells.

University of Minnesota Team Harnesses the Power of Stem Cells to Repair the Brain and Spinal Cord

For years, doctors treating patients who had brain or spinal cord injury faced a terrible impasse.

ILS and Stemina Ally to Advance Human Embryonic Stem Cell Based Toxicology Testing

ILS and Stemina Biomarker Discovery entered into a partnership to advance Stemina's stem cell based toxicology testing tools, beginning with devTOX. ILS has exclusive distribution rights in North America, and the two firms will work jointly on further development.

Discovery May Help Produce Stem Cells

A new way to rejuvenate old stem cells raises the possibility that patients' own stem cells may one day be rescued and banked, U.S. researchers say.

'Mini' Stem Cell Transplant May Help Seniors With Blood Cancer

Age in itself should not be a factor in deciding whether blood cancer patients are candidates for stem cell transplantation, according to a new study.

Spinal Membrane As A Source Of Stem Cells May Advance Spinal Cord Treatment

Italian and Spanish scientists studying the use of stem cells for treating spinal cord injuries have provided the first evidence to show that meninges, the membrane which envelops the central nervous system, is a potential source of self-renewing stem cells. The research, published in STEM CELLS, develops the understanding of cell activation in central nervous system injuries; advancing research into new treatments for spinal injuries and degenerative brain disorders.

Researchers Find Regulatory T-Cell Clue to Help Prevent Graft-Versus-Host Disease

Graft-versus-host disease (GVHD) is a serious risk in many kinds of cell transplants, including for stem cell transplants carried out when stem cells are partially depleted of conventional T cells, which play an important role in the immune system. Now, researchers at Moffitt Cancer Center have tested a process by which T regulatory cells (Tregs) can be "expanded" to help prevent GVHD.

Growing Body Parts in a Jar

A new technology could offer hope for people in desperate need of an organ transplant. More than 100,000 American men, women and children currently need life-saving transplants. An average of 18 people die each day for lack of a suitable organ.

Grow Your Own Cure for Damaged Knees

Scientists in Scotland are planning to use stem cells to grow new cartilage to help patients who have suffered serious injury to their knees.

Regenerated Lungs from Stem Cells Bring Possible Therapy

Severe cases of the flu can trash lungs, leaving patients gasping for breath.

Artificial Blood Could Be Used Within Next Decade

Patients undergoing transplant operations could be given artificial blood produced from stem cells within the next decade, researchers claim.

Surgeons Develop Simultaneous Tissue and Stem Cell Transplant Technique

Surgical researchers at the University of Washington, Seattle, have pioneered a method using stem cells that may one day eliminate the need for antirejection drugs in transplants. Primary investigator David Mathes, MD, FACS, and his research fellow Jeff Chang, MD, MS, presented their findings today at the 2011 Clinical Congress of the American College Surgeons. Two groups of patients who might one day benefit from this early research breakthrough are hand and face transplant recipients. To date, survival of these transplants has depended on administering high-dose drugs to patients that suppress the immune system like those used in major organ transplants. However, these drugs are expensive and have a multitude of side effects, the researchers explained.

Technology to Collect Stem Cells from Fat Tissue may Help Soldiers Recover from Traumatic Injuries

Indiana-based engineering and life sciences companies have contracted with researchers at the University of Pittsburgh to adapt a technology that holds promise to help soldiers regrow tissue and recover from severe wounds.

Intestinal Stem Cells Respond to Food by Supersizing the Gut

A new study from University of California, Berkeley, researchers demonstrates that adult stem cells can reshape our organs in response to changes in the body and the environment, a finding that could have implications for diabetes and obesity.

Lab-made Skin Cells will Aid Transplantation, Cancer, Drug Discovery Research

The pigmented cells called melanocytes aren't just for making freckles and tans. Melanocytes absorb ultraviolet light, protecting the skin from the harmful effects of the sun. They also are the cells that go haywire in melanoma, as well as in more common conditions as vitiligo and albinism.

Heart Disease Research Breakthrough Sparks Cure Hope

Heart disease can now be mimicked in a petri dish in a medical breakthrough that could lead to new treatments for the biggest killer in the Western world.

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Events

Learn more about the promise of stem cell research -- join us at one of these upcoming events!

2012 Missouri Cures Education Foundation Speakers Series 

sponsored by
the Staenberg Family Foundation
in conjunction with THF Realty
& MedStem

Feb. 26, Columbia
Mark Kirk, Ph.D.

March 11, Kansas City
Dawn Cornelison, Ph.D.

April 15, Columbia
John Viator, Ph.D.

April 22, St. Louis
Marie Csete, M.D., Ph.D.

May Fund-raiser, St. Louis
Details TBA

June 10, St. Louis
Bill Miller, M.D.

August (date TBA), Springfield
John Viator, Ph.D.

Aug. 26, Kirksville
Dawn Cornelison, Ph.D.

Sept. 9, Columbia
Russell Swerdlow, M.D.

September, Kansas City
Details TBA

October Fund-raiser, St. Louis
Details TBA 

Learn more »

 


 

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Missouri Cures is dedicated to promoting and protecting medical research, including stem cell research.

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